3-DEOXYGLUCOSONE Property

Melting point:

73-75°C

Boiling point:

208.81°C (rough estimate)

Density 

1.2132 (rough estimate)

refractive index 

1.4230 (estimate)

RTECS 

MQ3390000

storage temp. 

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

solubility 

Methanol (Slightly), Water (Slightly, Sonicated)

form 

Solid

pka

13.17±0.20(Predicted)

color 

Yellow

Water Solubility 

Soluble in water, methanol or hot ethanol.

Stability:

Hygroscopic

Safety

Hazard Codes 

Xi

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29329990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

3-DEOXYGLUCOSONE Chemical Properties,Usage,Production

Description

3-deoxy Glucosone is a highly reactive 2-oxoaldehyde intermediate of the Maillard reaction produced during oxidative stress in response to excess sugar consumption and in association with diabetes. It is a precursor for the formation of advanced glycation endproducts and because it readily reacts with protein amino groups is also used for crosslinking studies. 3-deoxy Glucosone can be used as a reference for the analysis and detection of glucose degradation products and glycating agents.

Chemical Properties

Amorphous Yellow Solid

Uses

An intermediate in the Maillard reaction of proteins with glucose, which is metabolised to 3-Deoxyfructose. An intermediate in the formation of pyrraline, which might contribute to a pathological effect, such as carcinogenesis

Uses

Frequently used as a reference for the analysis and detection of glucose degradation products and glycating agents. Also used for cross-linking studies as it readily reacts with protein amino groups.

Definition

ChEBI: A deoxyketohexose comprising the open-chain form of D-glucose lacking the -OH group at the 3-position and having the keto group at the 2-position.